We’re on the road to therapeutics for hypertriglyceridemia. Read our new publication in the Journal of Lipid Research on the use of a Furin resistant LPL for use in protein replacement therapy. Find it at Pubmed.
Wu, M. J., Wolska, A., Roberts, B. S., Pearson, E. M., Gutgsell, A. R., Remaley, A. T., & Neher, S. B. (2018). Co-expression of Novel Furin-Resistant LPL Variants with LMF1 Enhances LPL Secretion and Activity. Journal of Lipid Research, 1(Dc), jlr.D086793. https://doi.org/10.1194/jlr.D086793